The reference site for Nabumetone

Nabumetone is a non-steroidal anti-inflammatory drug (NSAID). Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran.


Nabumetone is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), which are drugs with analgesic, antipyretic and anti-inflammatory effects – they reduce pain, fever and inflammation. Nabumetone works by reducing hormones that cause swelling and pain in the body.

This medication is used to treat the symptoms of osteoarthritis and rheumatoid arthritis.


Brand Name(s): Relafen
CAS nº: 42924-53-8
(na byoo’ me tone)

Product Info

The sections below will provide you with more specific information and guidelines related to nabumetone and its correct use. Please read them carefully.

FDA Information

Nabumetone was approved by the Food and Drug Administration in December 1991.

Why is this medication prescribed?

Nabumetone is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), which are drugs with analgesic, antipyretic and anti-inflammatory effects – they reduce pain, fever and inflammation. Nabumetone works by reducing hormones that cause swelling and pain in the body.

This medication is used to treat the symptoms of osteoarthritis and rheumatoid arthritis.

Other uses for this medicine

Nabumetone  is also used to relieve gout, menstrual cramps, or other kinds of pain.

However, It is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Nabumetone comes as a tablet to take by mouth.

It is usually taken once or twice a day with or without food.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nabumetone exactly as directed.

Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

If you are taking nabumetone long-term, your blood will need to be tested on a regular basis. This is to make sure the medication is not causing harmful effects. It is important that you not miss any scheduled visits to your doctor.

What special precautions should I follow?


Tell your doctor if you have: a history of heart attack, stroke, or blood clot; heart disease, congestive heart failure or fluid retention problems; high blood pressure; asthma; a stomach ulcer or bleeding in the stomach or intestines; liver or kidney disease; or if you drink more than three alcoholic beverages a day. If you have any of these conditions, you may not be able to use nabumetone, or you may need a dosage adjustment or special tests during treatment.

Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal. These gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Do not take nabumetone if you have ever had an allergic reaction to aspirin or another NSAID such as ibuprofen (Motrin®, Advil®), diclofenac (Voltaren®), indomethacin, naproxen (Aleve®, Naprosyn®), piroxicam (Feldene®), etodolac (Lodine®), and others.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Nabumetone should not be taken during the third trimester of pregnancy because a similar drug is known to affect the baby’s heart.

It is not known whether nabumetone passes into breast milk or if it could harm a nursing baby Do not take this medicine without telling your doctor if you are breast-feeding a baby.

Avoid prolonged exposure to sunlight. Nabumetone may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Avoid drinking alcohol, or use it with moderation. If you drink more than three alcoholic beverages a day and are taking nabumetone, you may have an increased risk of dangerous stomach bleeding.

Avoid smoking, because it can increase your risk of stomach or intestinal bleeding.

What should I do if I forget a dose?

Nabumetone is sometimes taken only when needed, so you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What side effects can this medication cause?

Possible side effects from nabumetone include:

abdominal pain

Tell your doctor if any of these symptoms are severe or do not go away:

dizziness, headache, weakness, or tired feeling
mild nausea, gas, diarrhea, or constipation
white patches or sores inside your mouth or on your lips
ringing in your ears
dry mouth, increased sweating
sleep problems (insomnia)

If you experience any of the following symptoms, call your doctor immediately:

chest pain, shortness of breath, problems with vision, speech, or balance
sudden numbness or weakness, especially on one side of the body
bloody, black, or tarry stools
coughing up blood or vomit that looks like coffee grounds
stomach cramps, indigestion, or heartburn
confusion, seizure (convulsions)
a red, blistering, peeling skin rash
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
pale skin, unusual weakness
swelling in your hands or feet, rapid weight gain

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose


In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

stomach pain
decreased urination
shallow breathing

Product Images


Below you will find images and specific information on the principal types of nabumetone that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 500 MG
Imprint: RELAFEN 500

Strength(s): 500 MG
Imprint: 93 15
Manufacturer: TEVA USA

Strength(s): 750 MG
Imprint: E146
Manufacturer: EON LABS

Strength(s): 750 MG
Imprint: GP 159

Strength(s): 750 MG
Imprint: 93 16
Manufacturer: TEVA USA

Strength(s): 750 MG
Imprint: RELAFEN 750

Contact us

If you are interested to acquire this site, please contact us.